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10 result(s) for "Woodbury, Charles P"
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Nuggets From Nature
One of the pleasant aspects of my job as a Park Ranger is the opportunity to see and study wildlife in its own home.
Local-Scale Carbon Budgets and Mitigation Opportunities for the Northeastern United States
Economic and political realities present challenges for implementing an aggressive climate change abatement program in the United States. A high-efficiency approach will be essential. In this synthesis, we compare carbon budgets and evaluate the carbon-mitigation potential for nine counties in the northeastern United States that represent a range of biophysical, demographic, and socioeconomic conditions. Most counties are net sources of carbon dioxide (CO2) to the atmosphere, with the exception of rural forested counties, in which sequestration in vegetation and soils exceed emissions. Protecting forests will ensure that the region's largest CO2 sink does not become a source of emissions. For rural counties, afforestation, sustainable fuelwood harvest for bioenergy, and utility-scale wind power could provide the largest and most cost-effective mitigation opportunities among those evaluated. For urban and suburban counties, energy-efficiency measures and energy-saving technologies would be most cost effective. Through the implementation of locally tailored management and technology options, large reductions in CO2 emissions could be achieved at relatively low costs.
Local-Scale Carbon Budgets and Mitigation Opportunities for the Northeastern United States
Economic and political realities present challenges for implementing an aggressive climate change abatement program in the United States. A high-efficiency approach will be essential. In this synthesis, we compare carbon budgets and evaluate the carbon-mitigation potential for nine counties in the northeastern United States that represent a range of biophysical, demographic, and socioeconomic conditions. Most counties are net sources of carbon dioxide (CO2) to the atmosphere, with the exception of rural forested counties, in which sequestration in vegetation and soils exceed emissions. Protecting forests will ensure that the region's largest CO2 sink does not become a source of emissions. For rural counties, afforestation, sustainable fuelwood harvest for bioenergy, and utility-scale wind power could provide the largest and most cost-effective mitigation opportunities among those evaluated. For urban and suburban counties, energy-efficiency measures and energy-saving technologies would be most cost effective. Through the implementation of locally tailored management and technology options, large reductions in CO2 emissions could be achieved at relatively low costs.
Characterization of a cDNA Coding for Human Factor VII
Factor VII is a precursor to a serine protease that is present in mammalian plasma. In its activated form, it participates in blood coagulation by activating factor X and/or factor IX in the presence of tissue factor and calcium. Clones coding for factor VII were obtained from two cDNA libraries prepared from poly(A) RNA from human liver and Hep G2 cells. The amino acid sequence deduced from the cDNAs indicates that factor VII is synthesized with a prepro-leader sequence of 60 or 38 amino acids. The mature protein that circulates in plasma is a single-chain polypeptide composed of 406 amino acids. The amino acid sequence analysis of the protein and the amino acid sequence deduced from the cDNAs indicate that factor VII is converted to factor VIIa by the cleavage of a single internal bond between arginine and isoleucine. This results in the formation of a light chain (152 amino acids) and a heavy chain (254 amino acids) that are held together by a disulfide bond. The light chain contains a γ -carboxyglutamic acid (Gla) domain and two potential epidermal growth factor domains, while the heavy chain contains the serine protease portion of the molecule. Factor VII shows a high degree of amino acid sequence homology with the other vitamin K-dependent plasma proteins.
Quantitative Analysis of Melanoma-Associated Antigen p97 in Normal and Neoplastic Tissues
We have used two highly sensitive assays to quantitate p97, a protein associated with human melanoma, in cultured cells and normal adult, fetal, and neoplastic tissues. To measure p97 at the surface of intact cells, radiolabeled Fab fragments of a monoclonal antibody specific for p97 were used in a binding assay. To measure p97 in detergent-solubilized membrane preparations, we used a novel double-determinant immunoassay that uses two monoclonal antibodies to two distinct antigenic determinants of p97. These assays revealed that although p97 is present in small amounts in normal adult tissues, it is present in much larger amounts in most melanomas, in some other tumors (both benign and malignant), and in certain fetal tissues. We conclude that monoclonal antibodies to p97 may prove to be of value for the diagnosis and therapy of melanoma.
Letters To The Editor
The Post Office has a new, attractive reppresentation of our nation's bird, the bald eagle, on its new drop boxes. However, this depiction is incorrect. Although it has the white head, it lacks the white tail of the mature bald eagle.